Co-processed excipients for direct tableting of orodispersible tablets (ODTs)
نویسندگان
چکیده
منابع مشابه
A review of co-processed directly compressible excipients.
Direct compression is the preferred method for the preparation of tablets. The present review outlines the importance of the functionality of the directly compressible adjuvants in the formulation of tablets. The co-processing is the most widely explored method for the preparation of directly compressible adjuvants because it is cost effective and can be prepared in-house based on the functiona...
متن کاملPharmacie Globale International Journal of Comprehensive Pharmacy Recent Research on Co-processed Excipients for Direct Compression-a Review
INTRODUCTION Direct compression is the process of tabletting of a blend of ingredients, the compression mix, without a preliminary granulation or aggregation process. The compression mix contains the active pharmaceutical ingredient blended with one or more excipients.1 It has been estimated that less than 20 percent of pharmaceutical materials can be compressed directly into tablets. The rest ...
متن کاملDevelopment of directly compressible co-processed excipients for solid dosage forms
The tablets manufactured by direct compression method using co-processed excipient showed relatively better disintegration time and in vitro drug release, with omission of number of laborious steps as compared to tablets manufactured by conventional wet granulation method. Melt granulation technique is a potential alternative for the development of directly compressible adjuvants. Lactose and m...
متن کاملParmacokinetic evaluation of ibuprofen controlled release matrix tablets using hydrophilic Eudragit® polymer and co-excipients.
The present study was conducted to formulate controlled release dosage forms containing Ibuprofen with Eudragit® S 100 polymer. The tablets were formulated at three different ratios with the polymer to investigate the effect of different concentrations of polymer on in vitro drug release patterns/kinetics and in vivo absorption/pharmacokinetics. Pre-formulation studies were conducted including ...
متن کاملCharacterization and Evaluation of Spray Dried Co- Processed Excipients and Their Application in Solid Dosage Forms
Major challenge for tablet manufacture comes from the powder characteristics of the materials to be compressed. This in turn poses a challenge in achieving greater productivity and better quality product especially on the new generation high-speed machines. Advancement in directly compressible materials has come in the form of co processed spray dried materials. The present work evaluates and ...
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ژورنال
عنوان ژورنال: Farmacja Polska
سال: 2018
ISSN: 0014-8261
DOI: 10.32383/farmpol/118669